PKK deficiency in B cells prevents lupus development in Sle lupus mice.
Oleksyn D, Zhao J, Vosoughi A, Zhao JC, Misra R, Pentland AP, Ryan D, Anolik J, Ritchlin C, Looney J, Anandarajah AP, Schwartz G, Calvi LM, Georger M, Mohan C, Sanz I, Chen L.
Oleksyn D, et al.
Immunol Lett. 2017 May;185:1-11. doi: 10.1016/j.imlet.2017.03.002. Epub 2017 Mar 6.
Immunol Lett. 2017.
PMID: 28274793
Free PMC article.
We previously showed that protein kinase C associated kinase (PKK) is required for B1 cell development as well as for the survival of recirculating mature B cells and B-lymphoma cells. Here, we investigated the role of PKK in lupus development in a lupus mouse model …
We previously showed that protein kinase C associated kinase (PKK) is required for B1 cell development as well as for the survival of recirc …